Do IgG Allergy Tests Live Up to the Hype?

Navigating the realm of food allergies can be challenging, and individuals often seek answers through various tests.

With limited access to an allergist and frustration with wait times, many people are turning to at-home tests that can be ordered online. One such test, the IgG antibody food panel, has gained popularity, promising insights into potential food allergies. However, it's crucial to understand that the IgG antibody test doesn't hold the key to unraveling food allergies or intolerances.

Firstly, it's essential to differentiate between allergies and intolerances/sensitivities. Allergies involve the immune system's response to a specific food, potentially leading to severe reactions such as vomiting, hives, or in severe cases, anaphylaxis. On the other hand, conditions referred to as intolerances and sensitivities often manifest as digestive issues or discomfort due to difficulties in processing certain foods and are not triggered by the immune system.

The IgG food panel test, offered by various companies, claims to identify allergies and sensitivities by measuring Immunoglobulin G (IgG) antibody levels to multiple foods. The idea is that eliminating foods with high IgG antibody levels could alleviate various symptoms, from digestive issues to broader health concerns. These tests often return multiple, even dozens of foods to be removed from the diet, which can be extremely difficult and disruptive.

It is crucial to note that scientific evidence supporting the efficacy of the IgG antibody test is lacking. The studies provided to endorse the test are often outdated, published in non-reputable journals, and may not even use the specific IgG antibody test in question. Moreover, the presence of IgG antibodies is a normal, healthy response to food exposure and high IgG antibody levels are likely to be found for any food the patient is eating regularly. In addition, since sensitivities and intolerances are not caused by the immune system, they cannot be identified through any antibody testing, including IgG antibody testing.

Major medical organizations, including the American Academy of Allergy, Asthma & Immunology and the Canadian Society of Allergy and Clinical Immunology, advise against using IgG testing for diagnosing food allergies or intolerances. The lack of substantial evidence raises concerns about the test's reliability and potential for misleading results.

While the desire for a straightforward solution to dietary discomfort is understandable, the current evidence suggests that relying on unproven tests may lead to unnecessary food restrictions, potential nutrient deficiencies, and heightened anxiety about eating. Seeking guidance from healthcare professionals, such as registered dietitians, can provide a more reliable and personalized approach to managing digestive symptoms.

In conclusion, while the quest for answers to food-related concerns is natural, it's essential to approach testing with a critical mindset. The IgG food panel, despite its widespread availability, lacks scientific validation and may not provide the clarity individuals seek. Seeking professional guidance and adopting a cautious approach to dietary changes can contribute to more informed and beneficial outcomes for overall well-being.

All health-related content on this website is for informational purposes only and does not create a doctor-patient relationship. Always seek the advice of your own pediatrician in connection with any questions regarding your baby’s health.

These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease. 

Dr. Erika Nolte, PhD

Dr. Nolte is the Science Director at Ready. Set. Food!

Next
Next

Understanding IgE Testing in Food Allergies